Three new bioactive flavonoid glycosides from Viscum album

Publication date: July 2019Source: Chinese Journal of Natural Medicines, Volume 17, Issue 7Author(s): Jia-Kun DAI, Duo CAO, Cui-Hua LI, Jing GAO, Meng-Qing LI, Na FAN, Ya-Hui WEI, Zheng-Liang SUN, Meng-Yang HOUABSTRACTTwo new flavonoid glycosides, named viscumneoside XII (1), and viscumneoside XIII (2); a new dihydrogen flavonoid glycoside product named viscumneoside XIV (3), were isolated from the aerial part of Viscum album, along with seven known compounds (4−10). Their structures were identified by analysis of spectroscopic data. In addition, cytotoxicity assay showed that 1, 2 and 3 possessed significant inhibitory activities against C6, A549 and MDA-MB-231 (the inhibition rate arrived about 50%, 70% and 74% respectively with IC50 ≤ 60.00 μmol·L−1), while the inhibition of TF-1 and Hela was not significant.
Source: Chinese Journal of Natural Medicines - Category: Complementary Medicine Source Type: research