Tumor necrosis factor alpha inhibits ovulation and induces granulosa cell death in rat ovaries

Conclusions Our data indicated that TNFα is an important mediator of ovulation in terms of decreasing the number of released oocytes and inducing granulosa cell death of unruptured follicles via apoptosis and autophagy for remodeling ovarian tissues.
Source: Reproductive Medicine and Biology - Category: OBGYN Source Type: research