Interleukin-13 Is Unlucky for Allergy Sufferers

Publication date: Available online 5 September 2019Source: Trends in Pharmacological SciencesAuthor(s): Markus M. Xie, Alexander L. DentAnaphylaxis, a life-threatening allergic reaction, is dependent on high affinity allergen-specific IgE. Gowthaman et al. now show that a new interleukin (IL)-13-expressing T helper cell subset specifically promotes high-affinity IgE responses. The discovery of T follicular helper (Tfh)13 cells defines potential new targets for allergy therapies.
Source: Trends in Pharmacological Sciences - Category: Drugs & Pharmacology Source Type: research