Topologic Analysis of Plasma Mitochondrial DNA Reveals the Coexistence of Both Linear and Circular Molecules [Molecular Diagnostics and Genetics]

CONCLUSIONS:
Linear and circular mtDNA molecules coexist in plasma and may have different tissue origins.

Source: Clinical Chemistry - September 2, 2019 Category: Chemistry Authors: Ma, M.-J. L., Zhang, H., Jiang, P., Sin, S. T. K., Lam, W. K. J., Cheng, S. H., Lee, W.-S., Gai, W., Tse, O. Y. O., Peng, W., Wong, J., Raghupathy, R., Wong, R. S. M., Sahota, D., Leung, T. Y., Chan, K. C. A., Chiu, R. W. K., Lo, Y. M. D. Tags: Molecular Diagnostics and Genetics Source Type: research