Anti Müllerian Hormone (AMH) level and expression in mural and cumulus cells in relation to age

This study investigates AMH level in the follicular fluid (FF) and mRNA expression pattern in cumulus and mural granulosa cells of human ovarian follicles in relation to age. Methods: We conducted a prospective study. Sixty-eight women undergoing In vitro fertilization (IVF) treatment were enrolled in the study. We obtained FF, mural and cumulus granulosa cells from large preovulatory follicles (17-20?mm) of 21?35 years old women (n?=?40) and 40?45 years old women (n?=?28) during oocyte pickup. Results: Higher level of AMH mRNA expression in cumulus cells was observed in the older age group compared to the younger (P
Source: Journal of Ovarian Research - Category: Cancer & Oncology Authors: Source Type: research