Initial Diagnosis and Staging of Pancreatic Cancer Including Main Differentials

Publication date: Available online 30 August 2019Source: Seminars in Ultrasound, CT and MRIAuthor(s): Axel Dallongeville, Lucie Corno, Stéphane Silvera, Isabelle Boulay-Coletta, Marc ZinsAbstractComputed Tomography remains the optimal imaging modality for both diagnosis and staging of pancreatic adenocarcinoma. Especially, CT is highly accurate in assessing the relationship of the tumor to critical arterial and venous structures, since their involvement can preclude surgical resection or indicate a neoadjuvant strategy in borderline resectable or locally advanced lesions. MRI provides additional staging information in isodense tumors or regarding presence of small liver metastases not seen at CT. Endoscopic ultrasound is the reference technique to be used for obtaining histologic proof. The introduction of perfusion modalities and radiomics may benefit the evaluation of pancreatic lesion parameters, thus helping to rule out differentials. However, these techniques require further investigation and standardization.
Source: Seminars in Ultrasound, CT and MRI - Category: Radiology Source Type: research