Investigating gains in neurocognition in an Intervention Trial of Exercise (IGNITE): Protocol
Despite the ubiquity of normal age-related cognitive decline there is an absence of effective approaches for improving neurocognitive health. Fortunately, moderate intensity exercise is a promising method for improving brain and cognitive health in late life, but its effectiveness remains a matter of skepticism and debate because of the absence of large, comprehensive, Phase III clinical trials. Here we describe the protocol for such a randomized clinical trial called IGNITE (Investigating Gains in Neurocognition in an Intervention Trial of Exercise), a study capable of more definitively addressing whether exercise influences cognitive and brain health in cognitively normal older adults.
Source: Contemporary Clinical Trials - Category: Radiology Authors: Kirk I. Erickson, George A. Grove, Jeffrey M. Burns, Charles H. Hillman, Arthur F. Kramer, Edward McAuley, Eric D. Vidoni, James T. Becker, Meryl A. Butters, Katerina Gray, Haiqing Huang, John M. Jakicic, M. Ilyas Kamboh, Chaeryon Kang, William E. Klunk, Source Type: research