Expression and significance of PTEN and GLUT-1 in proliferative endometrium, endometrial hyperplasia, and endometrioid adenocarcinoma

Conclusion: Lack of PTEN expression and overexpression of GLUT-1 may be early events in the tumorigenesis of endometrioid adenocarcinoma. The combination of PTEN-negative/GLUT-1-positive results may be useful in distinguishing benign hyperplasia from endometrial intraepithelial neoplasia and endometrioid adenocarcinoma.
Source: Egyptian Journal of Pathology - Category: Pathology Tags: Original Articles Source Type: research