Neuropathogenic Escherichia coli K1 does not exhibit proteolytic activities to exert its pathogenicity

Conclusions: Neither zymographic assays nor protease assays detected proteolytic activities in either the whole bacteria or conditioned media of E. coli K1 strain E44 and E. coli K-12 strain HB101. These findings suggest that host cell monolayer disruptions and immune evasion strategies are likely independent of proteolytic activities of neuropathogenic E. coli K1.
Source: Journal of Negative Results in BioMedicine - Category: Research Authors: Source Type: research