Antidepressant effects of ginsenoside Rf on behavioral change in glial degeneration model of depression by reversing glial loss

ConclusionG-Rf markedly reversed depressive-like behavioral changes and exhibited protective effect against the astrocyte ablation in PFC induced by L-AAA. These protective properties suggest that G-Rf might be a therapeutic agent for major depressive disorder.Graphical abstract
Source: Journal of Ginseng Research - Category: Complementary Medicine Source Type: research