Explanation for different behavior of peripheral and central giant cell granuloma by CD44 and CD34 immunostaining

ConclusionDifferent CD44 expression among the studied groups may be indicative of the different motility of osteoclastic giant cells which may influence bone resorption. Lower CD44 expression probably indicates higher osteoclastic giant cell motility in CGCG, which with its higher angiogenesis may explain the different clinical behavior of CGCG compared with that of PGCG.

Source: Journal of Investigative and Clinical Dentistry - August 20, 2019 Category: Dentistry Authors: Massoumeh Zargaran, Fahimeh Baghaei, Abbas Moghimbeigi, Fereshteh Baghai Tags: ORIGINAL ARTICLE Source Type: research