Extracellular matrix protein 1 regulates cell proliferation and trastuzumab resistance through activation of epidermal growth factor-signaling

Conclusions:
ECM1 has important roles in both cancer development and trastuzumab resistance in breast cancer through activation of EGFR signaling.

Source: Breast Cancer Research - December 11, 2014 Category: Cancer & Oncology Authors: Kyung-min LeeKeesoo NamSunhwa OhJuyeon LimYoung-Pil KimJong LeeJong-Han YuSei-Hyun AhnSung-Bae KimDong-Young NohTaehoon LeeIncheol Shin Source Type: research