Brentuximab vedotin, doxorubicin, vinblastine, and dacarbazine for nonbulky limited-stage classical Hodgkin lymphoma
In conclusion, brentuximab-AVD without bleomycin or radiation produced a high complete response rate, with most patients requiring only 4 total cycles of therapy. Because toxicity was higher than would be expected from AVD alone, this method may not be appropriate for early-stage patients with a highly favorable prognosis. This trial was registered at www.clinicaltrials.gov as #NCT01534078.
Source: Blood - Category: Hematology Authors: Abramson, J. S., Arnason, J. E., LaCasce, A. S., Redd, R., Barnes, J. A., Sokol, L., Joyce, R., Avigan, D., Neuberg, D., Takvorian, R. W., Hochberg, E. P., Bello, C. M. Tags: Lymphoid Neoplasia, Clinical Trials and Observations Source Type: research
More News: Brain | Clinical Trials | CT Scan | Hematology | Lymphoma | Neurology | Peripheral Neuropathy | PET Scan | Study | Toxicology