Stereoisomer-specific ginsenoside 20(S)-Rg3 reverses replicative senescence of human diploid fibroblasts via Akt-mTOR-Sirtuin signaling

ConclusionCellular molecular analysis suggests that Rg3(S) specifically reverses the replicative senescence of HDFs by modulating Akt-mTOR-Sirtuin signaling to promote the biogenesis of mitochondria.Graphical abstract
Source: Journal of Ginseng Research - Category: Complementary Medicine Source Type: research