Variability in C-type lectin receptors regulates neuropathic pain-like behavior after peripheral nerve injury

Conclusion: We here for the first time demonstrate that C-type lectins, a family of innate immune receptors with largely unknown functions in the nervous system, are involved in regulation of inflammation and development of neuropathic pain behavior after nerve injury. Further experimental and clinical studies are needed to dissect the underlying mechanisms more in detail as well as any possible relevance for human conditions.
Source: Molecular Pain - Category: Molecular Biology Authors: Source Type: research