Mild Cognitive Impairment and Exposure to General Anesthesia for Surgeries and Procedures: A Population-Based Case-Control Study

(Abstracted from Anesth Analg, 124(4):1277–1290, 2017) The purpose of this article was to use a case-control design to prove or disprove the hypothesis that exposure to general anesthesia for surgery and procedures in patients 40 years or older is associated with prevalent mild cognitive impairment (MCI) and analysis to find the connection between general anesthesia in the “aged” (defined here as ≥40 years) and cognitive impairment (eg, MCI, dementia). Preclinical studies indicate that some general anesthesia drugs may cause neurohistologic changes consistent with Alzheimer dementia.
Source: Survey of Anesthesiology - Category: Anesthesiology Tags: General Anesthesia Source Type: research