Genetic and epigenetic analyses of aldosterone-producing adenoma with hypercortisolemia

In conclusion, the genetic analysis revealed no association between hypercortisolemia and the evaluated gene mutations. However, the epigenetic analysis suggested that DNA methylation of the CYP11B1 promoter plays a role in concurrent hypercortisolemia and APA.
Source: Steroids - Category: Drugs & Pharmacology Source Type: research