Synthesis, characterization, and in vitro evaluation of gamma radiation-induced PEGylated isoniazid

ConclusionsIn summary, the research suggests that it is possible to covalently attach the PEG onto INH by the proposed method and to obtain a slow-acting isoniazid derivative with little toxicity in vitro and higher anti-mycobacterial potency than the neat drug.
Source: Electronic Journal of Biotechnology - Category: Biotechnology Source Type: research