Endothelial life discontinues without Erk

The mechanism of maintaining vascular endothelial identity and integrity is largely unknown. In this issue of JEM, Ricard et al. (https://doi.org/10.1084/jem.20182151) discover essential roles of ERK1/2 in maintaining endothelial homeostasis and its deletion-related serious defects in multiple tissues and organs.
Source: The Journal of Experimental Medicine - Category: Internal Medicine Authors: Tags: Cardiovascular Biology, Stem Cells & Regeneration Insights Source Type: research