Prevalence and phenotypes of JAK2 V617F and calreticulin mutations in a Danish general population

In conclusion, we present a novel population prevalence of CALR and a JAK2 V617F prevalence that is 3 to 30 times higher compared with less sensitive methods. Mutation-positive non-MPNs with elevated blood cell counts raise concerns of MPN underdiagnosis in the population.

Source: Blood - July 31, 2019 Category: Hematology Authors: Cordua, S., Kjaer, L., Skov, V., Pallisgaard, N., Hasselbalch, H. C., Ellervik, C. Tags: Hematopoiesis and Stem Cells, Myeloid Neoplasia Source Type: research