Roles of FtsEX in cell division

Publication date: Available online 1 August 2019Source: Research in MicrobiologyAuthor(s): Sebastien Pichoff, Shishen Du, Joe LutkenhausAbstractFtsEX is a member of a small subclass of ABC transporters that uses mechano-transmission to perform work in the periplasm. FtsEX controls periplasmic peptidoglycan (PG) hydrolase activities in many Gram negative and positive organisms to ensure the safe separation of daughter cells during division. FtsEX localizes to the Z ring and uses its ATPase activity to regulate its periplasmic effectors. In E. coli, FtsEX also participates in building the divisome and coordinates PG synthesis with PG hydrolysis. This review discusses studies that are beginning to elucidate the mechanisms of FtsEX’s various roles in cell division.
Source: Research in Microbiology - Category: Microbiology Source Type: research