Effect of PPARβ/δ Agonist on the Placentation and Embryo‐Fetal Development in Rats

CONCLUSIONSHigh frequency of placental malformation was observed by the administration of GW501516. From GD 8 to 11, especially GD 10, is more sensitive period to induce the placental malformation.

Source: Birth Defects Research Part B: Developmental and Reproductive Toxicology - March 4, 2013 Category: Perinatology & Neonatology Authors: Kyohei Nishimura, Nao Nakano, Vishwajit Sur Chowdhury, Masako Kaneto, Mikinori Torii, Masa‐aki Hattori, Nobuhiko Yamauchi, Motoyuki Kawai Tags: Original Article Source Type: research