The Teratogenic Effect of Dofetilide during Rat Limb Development and Association with Drug‐Induced Bradycardia and Hypoxia in the Embryo

CONCLUSIONSDrugs that induce periods of bradycardia and/or arrhythmia of the embryonic heart and cause the embryo to become hypoxic are potential human teratogens.

Source: Birth Defects Research Part B: Developmental and Reproductive Toxicology - March 15, 2013 Category: Perinatology & Neonatology Authors: Helen E. Ritchie, Deena H. Ababneh, Diana J. Oakes, Carl A. Power, William S. Webster Tags: Original Article Source Type: research