Experimental designs for a Benign Paroxysmal Positional Vertigo model

Conclusions: A biomechanical model was derived to provide a quantitative basis for the detection of BPPV. The robustness study for the D-optimal design, with respect to the choice of the nominal values of the parameters, shows high efficiencies for small variations and provides a guide to the researcher.Furthermore, c-optimal designs give valuable assistance to check how efficient the D-optimal design is for the estimation of each of the parameters. The experimental designs provided in this paper allow the physician to validate the model. The authors of the paper have held consultations with an ENT consultant in order to align the outline more closely to practicalscenarios.Key wordsBPPV, c-optimal design, D-optimal design, Efficiency, Information Matrix.
Source: Theoretical Biology and Medical Modelling - Category: Biomedical Science Authors: Source Type: research