Centralized, stepped, patient preference-based treatment for patients with post-acute coronary syndrome depression: CODIACS Vanguard randomized controlled trial

Source: JAMA Internal Medicine Area: Evidence > Medicines Management > References Importance: Controversy remains about whether depression can be successfully managed after acute coronary syndrome (ACS) and the costs and benefits of doing so. Objective: To determine the effects of providing post-ACS depression care on depressive symptoms and health care costs. Design: Multicentre, randomised, controlled trial. Setting: Patients were recruited from 2 private and 5 academic ambulatory centres across the United States. Participants: A total of 150 patients with elevated depressive symptoms (Beck Depression Inventory (BDI) score 10 or higher) 2 to 6 months after an ACS, recruited between 18 Mar 2010 and 9 Jan 2012. Interventions  Patients were randomised to 6 months of centralised depression care (patient preference for problem-solving treatment given via telephone or the Internet, pharmacotherapy, both, or neither), stepped every 6 to 8 weeks (active treatment group; n = 73), or to locally determined depression care after physician notification ...
Source: NeLM - Mental Health - Category: Psychiatry Source Type: news