A mixed state core for melancholia: an exploration in history, art and clinical science.
CONCLUSION: These findings and considerations overall do suggest that melancholia as defined today is more closely aligned with the depressive and/or mixed phase of bipolar disorder. Given the high suicidality from many of these patients the practice of treating them with antidepressant monotherapy needs re-evaluation.
PMID: 17280570 [PubMed - indexed for MEDLINE]
Source: Acta Psychiatrica Scandinavica Supplementum - Category: Psychiatry Tags: Acta Psychiatr Scand Suppl Source Type: research
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