Effect of antioxidant vitamin supplementation on cardiovascular outcomes: A meta-analysis of randomised controlled trials

Source: PLoS One Area: News According to the findings of this systematic review and meta-analysis of pooled data from randomised controlled trials (RCTs), antioxidant vitamin supplementation has no effect on the incidence of major cardiovascular events, myocardial infarction, stroke, total death, and cardiac death.   Data (published and unpublished) for the analysis were sourced through a search of databases such as PubMed, EmBase the Cochrane Central Register of Controlled Trials and conference reports. Studies were included if they were RCTs that reported on the effects of antioxidant vitamins on cardiovascular outcomes vs.  placebo. Overall a total of 293 studies were identified and of these 15 trials were included in the analysis (n=188,209). Of the RCTs included, 7 trials evaluated antioxidant vitamin supplementation in participants with high cardiovascular risk factors or previous cardiovascular disease, and the remaining 8 trials reported individuals without high cardiovascular risk ...
Source: NeLM - Cardiovascular Medicine - Category: Cardiology Source Type: news