Exelon (rivastigmine) patches - all strengths - Novartis Pharmaceuticals UK Ltd - revised SPC

Source: eMC (electronic Medicines Compendium) Area: Other Library Updates > SPC Changes Section 4.2 Posology and method of administration has been updated to state that 9.5 mg/24 hours is the recommended daily effective dose which should be continued for as long as the patient continues to demonstrate therapeutic benefit. If well tolerated and only after a minimum of six months of treatment at 9.5 mg/24 hours, the treating physician may consider increasing the dose to 13.3 mg/24 hours in patients who have demonstrated a meaningful cognitive deterioration (e.g. decrease in the MMSE) and/or functional decline (based on physician judgement) while on the recommended daily effective dose of 9.5 mg/24 hours.   Section 4.4 had previously stated that if treatment is interrupted for more than several days, it should be re-initiated with 4.6 mg/24 hours. This has been updated to specify more than three days.   Please see link to the SPC for full prescribing information
Source: NeLM - Mental Health - Category: Psychiatry Source Type: news