Gastrointestinal Stromal Tumor (GIST) from esophagus to anorectum & #8211; diagnosis, response evaluation and surveillance on computed tomography (CT) scan

Sushil N Panbude, Suman K Ankathi, Anant T Ramaswamy, Avanish P SaklaniIndian Journal of Radiology and Imaging 2019 29(2):133-140
Gastrointestinal stromal tumor (GIST) are the most common non epithelial tumor of the gastrointestinal (GI) tract. They arise from interstitial cells of Cajal present in the myenteric plexus. They can also arise outside the GI tract from mesentery, retro peritoneum and omentum. With the advent of new targeted molecular therapy c- tyrosine kinase inhibitor (Imatinib), it has become important to differentiate between response and pseudo-progression of the disease as response evaluation criteria for GIST are different from Response Evaluation Criteria in Solid Tumors (RECIST). Purpose of this pictorial essay is to enumerate the characteristic CT features of GIST, and discuss atypical features and response evaluation criteria.

Source: Indian Journal of Radiology and Imaging - July 8, 2019 Category: Radiology Authors: Sushil N Panbude Suman K Ankathi Anant T Ramaswamy Avanish P Saklani Source Type: research