Muscle injury promotes heterotopic ossification by stimulating local bone morphogenetic protein-7 production

ConclusionIn summary, our study has identified BMP-7 as a key osteoinductive factor in injured muscle that facilitates HO formation.The translational potential of this articleOur results provide a candidate mechanistic rationale for the use of antiinflammatory drugs in the prevention of HO.
Source: Journal of Orthopaedic Translation - Category: Orthopaedics Source Type: research