Pediatric Evans syndrome is associated with a high frequency of potentially damaging variants in immune genes

In conclusion, pES was potentially genetically determined in at least 65% of cases. Systematic, wide-ranging genetic screening should be offered in pES; the genetic findings have prognostic significance and may guide the choice of a targeted treatment.

Source: Blood - July 3, 2019 Category: Hematology Authors: Hadjadj, J., Aladjidi, N., Fernandes, H., Leverger, G., Magerus-Chatinet, A., Mazerolles, F., Stolzenberg, M.-C., Jacques, S., Picard, C., Rosain, J., Fourrage, C., Hanein, S., Zarhrate, M., Pasquet, M., Abou Chahla, W., Barlogis, V., Bertrand, Y., Pellie Tags: Pediatric Hematology, Immunobiology and Immunotherapy, Platelets and Thrombopoiesis, Red Cells, Iron, and Erythropoiesis, Clinical Trials and Observations Source Type: research