CADTH review of the clinical effectiveness of thrombolytic drugs for cardiac arrest

Source: Canadian Agency for Drugs and Technologies in Health (CADTH) Area: News This Canadian review looks at the clinical effectiveness of thrombolytic drugs in people experiencing cardiac arrest.   A limited literature search of the literature identified three publications suitable for inclusion - one systematic review and two observational studies. The authors summarise the findings of each of the included publications and discusses the limitations of the currently available evidence in this area.   Based on the evidence included in the review, the authors conclude that while thrombolytics may increase the likelihood of return of spontaneous circulation and survival to hospital admission, they do not appear to increase the likelihood of survival to hospital discharge or 30 days after cardiac arrest compared to placebo or standard care. In addition, use of thrombolytics increased bleed risk, including intracranial haemorrhage, compared to placebo. Please see the link below for details.
Source: NeLM - Cardiovascular Medicine - Category: Cardiology Source Type: news