Expecto Patronin for slow and persistent minus end microtubule growth in dendrites

Microtubule plus ends are highly dynamic in neurons, while minus ends are often capped and stable. In this issue, Feng et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201810155) demonstrate that in dendrites, free minus ends undergo slow and processive growth mediated by the minus end–binding protein Patronin.

Source: Journal of Cell Biology - June 30, 2019 Category: Cytology Authors: Broihier, H. T. Tags: Spotlight Source Type: research