Thyroid hormones for acute kidney injury

Source: Cochrane Area: Evidence > Drug Specific Reviews Background Acute kidney injury (AKI), which is common in hospitalised patients, is associated with significant morbidity and mortality. Despite recent advances in treatment, AKI outcomes have not changed substantially during the past four decades, and incidence is increasing. There is an urgent need to explore novel therapeutic agents and revisit some older drugs to review their roles in the management of AKI. Although thyroid hormone therapy has shown promise in experimental animal studies, clinical efficacy and safety have not been systematically assessed for the management of people with AKI.     Objectives To evaluate the benefits and harms of thyroid hormones for the treatment of hospitalised adults with AKI of any aetiology.   Search methods We searched the Cochrane Renal Group's Specialised Register, CENTRAL, MEDLINE, and EMBASE. We also checked the reference lists of retrieved studies and articles. Date of search: November ...
Source: NeLM - Drug Specific Reviews - Category: Drugs & Pharmacology Source Type: news