Meta-analysis: Efficacy of cytisine for smoking cessation

Source: Thorax Area: News Thorax has featured a meta-analysis of studies evaluating cytisine for smoking cessation.   A recent study had shown that cytisine, a low-cost drug, is effective for smoking cessation. A number of earlier studies exist, and cytisine was previously used - however, this meta-analysis was undertaken to assess the efficacy of cytisine in smoking cessation and to assess whether there is sufficient evidence to warrant licensing cytisine or whether more work is needed.   After a search on the Cochrane Library, CINAHL, Embase, Medline and PsycINFO databases, 7 controlled trials were identified which met inclusion criteria. Two separate meta-analyses were conducted: The first considered the strictest definition of outcome and longest follow-up from all available studies and the second pooled outcomes from studies with biochemically validated abstinence and follow-up of 6 months or longer.   The following results were reported: . When pooled (first ...
Source: NeLM - News - Category: Drugs & Pharmacology Source Type: news