Antibody-Drug Conjugates and Immunotoxins

From Pre-Clinical Development to Therapeutic Applicationsseries:Cancer Drug Discovery and DevelopmentThe concept of delivering ‘magic bullets’ to treat diseases was first proposed by Paul Erlich in the early 1900’s.  The realization of this concept for the treatment of cancer occurred in the late 1990’s with the approval of monoclonal antibody therapies.  The use of monoclonal antibodies conjugated (linked) to potent cytotoxic agents (antibody-drug conjugates, ADCs) for specifically ...
Source: Springer Biomedical Sciences titles - Category: Biomedical Science Tags: Cancer Research Source Type: news