A case of refractory serum sodium disorders with severe multiple trauma

Publication date: Available online 21 June 2019Source: Personalized Medicine UniverseAuthor(s): Kasumi Satoh, Tomoki Furuya, Manabu Okuyama, Hajime NakaeAbstractA 40-year-old man was admitted to the hospital with multiple injuries, including head injury and his laboratory results were significant for sodium abnormalities. Initially, hypernatremia was from increased sodium intake. Subsequently, hyponatremia developed that was unresponsive to sodium supplementation. Syndrome of inappropriate antidiuretic hormone secretion or cerebral salt wasting syndrome was suspected. Additional tests suggested post-traumatic hypopituitarism was responsible for the hyponatremia. Corticosteroid were given which normalized the serum sodium level, but the urine volume increased. Masked diabetes insipidus was suspected and desmopressin was given, stabilizing the serum sodium level. Recognizing the factors that cause sodium abnormalities in trauma patients can help lead to the correct diagnosis.
Source: Personalized Medicine Universe - Category: Drugs & Pharmacology Source Type: research