Kallikrein family proteases KLK6 and KLK7 are potential early detection and diagnostic biomarkers for serous and papillary serous ovarian cancer subtypes

Conclusion:
KLK6 and KLK7 mRNA and protein overexpression is directly associated with early-stage ovarian tumors and can be measured in patient tissue and serum samples. Assays based on KLK6 and KLK7 expression may provide specific and sensitive information for early detection of ovarian cancer.

Source: Journal of Ovarian Research - December 5, 2014 Category: Cancer & Oncology Authors: Ayala TamirUshma JagSreeja SarojiniCraig SchindewolfTakemi TanakaRajendra GharbaranHiren PatelAnil SoodWei HuRuzeen PatwaPatrick BlakePolina ChirinaJin Oh JeongHeejin LimAndre GoyAndrew PecoraK Suh Source Type: research