Modulation of tumor fatty acids, through overexpression or loss of Thyroid Hormone Responsive Protein Spot 14, is associated with altered growth and metastasis

Conclusions: This study demonstrates a potential role for S14 in regulating mammary tumor growth and fatty acid synthesis in vivo. Furthermore, these results suggest that modulating the amount of medium chain fatty acids, by changing the levels of S14, has the potential to impact malignant mammary tumor phenotypes.
Source: Breast Cancer Research - Category: Cancer & Oncology Authors: Source Type: research