Oral leiomyomatous hamartoma associated with upper lip midline malformation: Case report and review of the literature

Abstract: A 3-month-old male patient presented an upper lip malformation associated to a polypoid nodule in the maxillary anterior alveolar ridge. Microscopically, the nodule was predominantly composed by a non-encapsulated smooth muscle proliferation intermingled by numerous blood vessels of varied sizes and scattered small nerve fibers. The smooth muscle tissue was positive for desmin and smooth muscle actin, while endothelial cells were highlighted by CD34 staining. The final diagnosis was of an oral leiomyomatous hamartoma associated with upper lip malformation. After surgical treatment, no recurrence has been observed after 2 years of follow-up.

Source: International Journal of Pediatric Otorhinolaryngology Extra - January 14, 2013 Category: ENT & OMF Authors: Saulo Gabriel Moreira Falci, Ana Terezinha Marques Mesquita, Mário José Romañach, Oslei Paes de Almeida, Cássio Roberto Rocha dos Santos Tags: Case reports Source Type: research