Rosuvastatin Changes Cytokine Expressions in Ischemic Territory and Preserves Heart Function After Acute Myocardial Infarction in Rats

Conclusion:
The data suggest that rosuvastatin can protect the heart from ischemic injury and preserve the cardiac function in rats in vivo. The changing expressions of SDF-1, CXCR-4, ICAM-1, and VEGF, and the accumulation of progenitor cells were involved in this process.

Source: Journal of Cardiovascular Pharmacology and Therapeutics - February 4, 2013 Category: Cardiology Authors: Hu, X., Sun, A., Xie, X., Huang, Z., Jia, J., Yao, R., Ge, J. Tags: Experimental Studies Source Type: research