Risk-Oriented Concept of Treatment for Intrathyroid Papillary Thyroid Cancer

Publication date: Available online 4 June 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Dana M. Hartl, Julien Hadoux, Joanne Guerlain, Ingrid Breuskin, Fabienne Haroun, Sophie Bidault, Sophie Leboulleux, Livia LamartinaAbstractAdapting treatment and follow-up according to the risk of recurrence and/or death from thyroid cancer is a relatively recent concept of “personnalized” medicine, developed particularly to avoid overtreatment of low-risk thyroid cancer which represents the majority of thyroid cancers diagnosed in the world today. For low-risk thyroid cancer, this decrease in extent of treatment involves the extent of surgery—total thyroidectomy, lobectomy or no surgery with active surveillance—but also the indications, doses and methods of stimulation when or if administering radioactive iodine (RAI), the indication for suppressive thyroxin therapy and the extent and modalities for follow-up that should be adapted to the risk of recurrence. The aim is to optimize medical resources and quality of life, particulary for low-risk patients whose life expectancy is that of the general population.
Source: Best Practice and Research Clinical Endocrinology and Metabolism - Category: Endocrinology Source Type: research