Close Link between Protoporphyrin IX Accumulation and Developmental Toxicity Induced by N‐Phenylimide Herbicides in Rats

CONCLUSIONSThe developmentally toxic compounds caused PPIX accumulation in embryos. The peak period of PPIX accumulation corresponded to that of developmental effects. This correlation suggests a close link between PPO inhibition and developmental abnormality
Source: Birth Defects Research Part B: Developmental and Reproductive Toxicology - Category: Perinatology & Neonatology Authors: Tags: Original Article Source Type: research