Radiotherapy resistance in chondrosarcoma cells; a possible correlation with alterations in cell cycle related genes

ConclusionsChondrosarcoma cell lines as well as primary tumors are variably radioresistant, particularly in case of a defective Rb pathway. Whether selection for radiotherapy can be based upon an intact Rb pathway should be further investigated.
Source: Clinical Sarcoma Research - Category: Cancer & Oncology Source Type: research