Generation of Highly Biomimetic Quality Control Materials for Noninvasive Prenatal Testing Based on Enzymatic Digestion of Matched Mother-Child Cell Lines [Molecular Diagnostics and Genetics]

CONCLUSIONS:
The DENQCMs are universally applicable for different platforms. We propose DENQCMs as an approach to produce matched maternal and fetal cfDNA that will be suitable for the preparation of quality control materials for NIPT.

Source: Clinical Chemistry - May 27, 2019 Category: Chemistry Authors: Zhang, R., Ding, J., Gao, P., Li, Z., Tan, P., Li, J. Tags: Molecular Diagnostics and Genetics Source Type: research