Suboptimal treatment adherence in bipolar disorder: impact on clinical outcomes and functioning

Source: Patient Preference and Adherence
Area: Evidence > Medicines Management > References
Background: The primary aim of this study was to assess drug treatment adherence in patients with bipolar disorder and to identify factors associated with adherence.  The secondary aim was to analyse the impact of suboptimal adherence on clinical and functional outcomes.
Methods: A cross-sectional study was conducted in a sample of outpatients receiving an oral antipsychotic drug.  Medication adherence was assessed combining the 10-item Drug Attitude Inventory, the Morisky Green Adherence Questionnaire, and the Compliance Rating Scale.  Logistic regression was used to determine significant variables associated with suboptimal adherence to medication.
Results: 303 patients were enrolled into the study.  The mean age was 45.9 +/- 12.8 years, and 59.7% were females.  69% of patients showed suboptimal adherence.  Disease severity and functioning were significantly worse in the suboptimal group than in the adherent group. ...

Source: NeLM - Mental Health - January 21, 2013 Category: Psychiatry Source Type: news