Expression of TMPRSS2/ERG oncoprotein in prostatic carcinoma: a correlative study with Gleason score and specimen type

Conclusion The higher the Gleason score, the lower the expression of ERG. Although ERG is encountered in the pathogenesis of Pca, it is not common to be overexpressed in Pca specimens, either radical prostatectomy or core biopsies. Despite many limitations of our study such as low number of specimens, the importance of ERG in prostatic carcinoma has to be further studied in association with other parameters such as PSA level and cancer staging.
Source: Egyptian Journal of Pathology - Category: Pathology Tags: ORIGINAL ARTICLES Source Type: research