Content and quality of 10,000 controlled trials in schizophrenia over 60 years

Source: Schizophrenia Bulletin Area: Evidence > Medicines Management > References Objective: To carry out an up-to-date comprehensive survey of the content and quality of intervention trials relevant to the treatment of people with schizophrenia. Design: Data were extracted and analysed from 10,000 trials on the Cochrane Schizophrenia Group's Register. Main Outcome Measures: Source, type and date of publication, country of origin, language, size of trial, interventions and outcome measures. Results: In the last decade, there has been a great increase in the number of trials relevant to schizophrenia and an improvement in the accessibility to reports.  The number of trials per year is rising (currently approx 600/year) with China now producing 25% of the annual total.  The number of reports of trials is increasing at an even greater rate due to multiple publications.  Drug trials still dominate (83%) although an increasing proportion of studies are now evaluating psychological therapies (21%).  Trials remain small (median 60 people) and ...
Source: NeLM - Mental Health - Category: Psychiatry Source Type: news