Temporal and spatial expression patterns of bone morphogenetic protein 3 in developing zebrafish.

Temporal and spatial expression patterns of bone morphogenetic protein 3 in developing zebrafish.
Open Rheumatol J. 2014;8:69-72
Authors: Ito-Amano M, Nakamura Y, Morisaki M, He X, Hayashi M, Watanapokasin R, Kato H
Abstract
Bone morphogenetic proteins (BMPs) are important elements in bone biology. We herein report the expression profiles of zebrafish bmp3 (zbmp3) as demonstrated by real-time PCR and in situ hybridization. The expression of zbmp3 was highly detectable by real-time PCR from 1 day post-fertilization (1 dpf) to 2 weeks post-fertilization (2 wpf) and peaked at 1 wpf. For in situ hybridization experiments, zbmp3 was expressed in the otic vesicle at 1 dpf, 2 dpf, 3 dpf, and 5 dpf. It was also expressed in the pharyngeal arches, including the opercle, branchiostegal ray, and pectoral fins, at 2 dpf. Our results suggest that zbmp3 may play an important role in the skeletal biology of developing zebrafish.
PMID: 25328556 [PubMed]

Source: Open Rheumatology Journal - December 2, 2014 Category: Rheumatology Tags: Open Rheumatol J Source Type: research