CCL22 controls immunity by promoting regulatory T cell communication with dendritic cells in lymph nodes

In conclusion, we identify the CCL22–CCR4 axis as an immune checkpoint that is crucial for the control of T cell immunity.

Source: The Journal of Experimental Medicine - May 5, 2019 Category: Internal Medicine Authors: Rapp, M., Wintergerst, M. W. M., Kunz, W. G., Vetter, V. K., Knott, M. M. L., Lisowski, D., Haubner, S., Moder, S., Thaler, R., Eiber, S., Meyer, B., Röhrle, N., Piseddu, I., Grassmann, S., Layritz, P., Kühnemuth, B., Stutte, S., Bourquin, Tags: Autoimmunity, Tumor Immunology Articles Source Type: research